Computational endoscopy
Detection, segmentation and quality assessment in GI endoscopy, with a focus on models that hold up across hospitals, devices and modalities.
PolypGen · EndoCV · TGANet · SSL-CPCD
AI in Medicine and Surgery · Leeds
I build computer vision methods that help clinicians see more inside the body: detecting and measuring disease in endoscopy, reconstructing organs in 3D, and guiding surgeons with augmented reality.
I am an Associate Professor in the School of Computer Science at the University of Leeds, where I founded and lead the AI in Medicine and Surgery (AIMS) group and am a member of the Leeds Cancer Research Centre. My work spans detection, segmentation, depth estimation, image registration, tracking and 3D reconstruction, using both classical and deep learning approaches, and is developed with gastroenterologists and surgeons in the NHS and abroad.
Before Leeds, I was a postdoctoral researcher at the University of Oxford's Department of Engineering Science (2018–2022), designing computer-assisted endoscopy models, and at Heidelberg University and DKFZ (2015–2018), where I developed physics-based deformable registration for 3D reconstruction of ultra-high-resolution brain histology. I received my PhD in image analysis from the Université de Lorraine (2016), on endoscopic video analysis for bladder cancer monitoring, and an MSc in Computer Vision from the Université de Bourgogne.
I have organised the EndoCV challenge series and MICCAI challenges on liver AR (P2ILF), co-organised the CaPTion and DEMI workshops at MICCAI, and served as General Chair of MIUA 2025. I sit on the steering committees of IEEE CBMS and MIUA and on the Royal Society Newton International Fellowships committee.
Two papers accepted at MICCAI 2026: Vis2Reg (landmark-free 3D–2D liver registration) and Bayesian Temporal Pose Networks for laparoscopic tool tracking.
Self-supervised monocular depth and pose estimation for endoscopy with latent priors published in IEEE Transactions on Medical Imaging.
DRENDS, a depth dataset for robotic endoscopy in dynamic scenes, published in Scientific Data.
New EPSRC award: Fibre 3D Endoscopy for Improved Clinical Surveillance; CRUK RadNet Leeds award on multi-modal MRI liver tissue maps.
Awarded the EPSRC New Investigator Award for real-time high-fidelity AR in laparoscopic liver resection, and the Academy of Medical Sciences Springboard Award.
General Chair of MIUA 2025, hosted in Leeds (15–17 July).
Congratulations to Dr Ziang Xu (Oxford) and Dr Xukun Zhang (Fudan) on completing their doctorates.
Listed among the Elsevier–Stanford World's Top 2% Scientists.
Detection, segmentation and quality assessment in GI endoscopy, with a focus on models that hold up across hospitals, devices and modalities.
PolypGen · EndoCV · TGANet · SSL-CPCD
Registering preoperative CT/MRI to the live laparoscopic view, tracking instruments, and building data for safer minimally invasive surgery.
P2ILF · Vis2Reg · NeeCo · tool pose
Monocular depth, pose and surface reconstruction from endoscopic video to measure lesions and map organs in 3D.
Col3D-MTL · latent-prior depth · DRENDS
Self-supervision, domain generalisation, out-of-distribution detection and vision–language models for IBD and cancer risk.
UC scoring · OOD · captioning
Infrared spectroscopy with statistical analysis and machine learning for cancer risk assessment in inflammatory bowel disease patients
E Kumi-Barimah, R Toman, A Jha, S Ali, V Subramanian
Analyst Scholar
LUX: A Lesion-Aware Graph-Conditioned Visual-Language Architecture for Explainable Endoscopic Captioning
AI Escamilla-Lopez, G Ochoa-Ruiz, S Hinojosa, S Ali
A Dataset for Depth in Robotic Endoscopy with Dynamic Scenarios (DRENDS)
G Loza-Galindo, M Magro, B Calmé, J Hu, E Ruffaldi, D Jones, E De Momi, et al.
Scientific Data 13 (1), 1163 Scholar
Vis2Reg: Visibility-Aware Landmark-Free Geometric 3D–2D Registration for Liver Laparoscopy
J Feng, X Zhang, S Farid, S Ali
Bayesian Temporal Pose Networks for Uncertainty-Calibrated Laparoscopic Tool Pose Tracking
O Choudhry, S Ali, CS Biyani, D Jones
MICCAI 2026 Scholar
DBMF: A Dual-Branch Multimodal Framework for Out-of-Distribution Detection
J Yue, D Treanor, V Subramanian, S Ali
Self-Supervised Vision Transformer for Surgical Phase Recognition in Endoscopic Submucosal Dissection
G Dutta, A Hammad, T Archer, Q Dou, N Mohammed, S Ali
IEEE ISBI 2026 Scholar
Patchsurg: Leveraging Synthetic Datasets for High-Fidelity Depth Estimation in Surgery
Z Xu, C Zhang, J Rittscher, S Ali
IEEE ISBI 2026 Scholar
GeoTranMesh: a geometry-guided multi-branch mesh transformer for 3D liver segmentation
J Feng, X Zhang, S Farid, S Ali
Int. J. Computer Assisted Radiology and Surgery Scholar
Self-supervised ultrasound-video segmentation with feature prediction and 3D localised loss
E Ellis, R Mendel, A Bulpitt, N Parsa, MF Byrne, S Ali
Medical Imaging 2026: Image Processing (SPIE) 13925 arXivScholar
A comprehensive multimodal dataset and benchmark for ulcerative colitis scoring in endoscopy
N Ghatwary, J Yue, A Elgendy, H Nagdy, A Galal, H Fathy, H El-Amin, et al.
Self-supervised Monocular Depth and Pose Estimation for Endoscopy with Latent Priors
Z Xu, B Li, Y Hu, C Zhang, J East, S Ali, J Rittscher
A multi-center analysis of deep learning methods for video polyp detection and segmentation
N Ghatwary, PC Solano, MR Ibrahim, A Krenzer, F Puppe, S Realdon, et al.
Automatic evaluation for knee angle measurement
S Hiyama, PE Chavarrias, S Ali, RP Rao, T Takahashi, V Shetty, J Tandel, et al.
Journal of Orthopaedic Reports, 100904 Scholar
General Surgery 4.0 – A Systematic Review of Extended Reality Interventions in General Surgery
MR Kowal, T Williams, A Dosis, S Pathak, S Farid, DD Stocken, P Lodge, et al.
Surgical Innovation Scholar
DEnPL: Improved Classification in Imbalanced Medical Datasets via Data-Engineered Prototypical Metric Loss
Z Wang, W Zang, Y Yuan, S Ali
MLMI 2025 (MICCAI Workshop) Scholar
Liver mask-guided SAM-enhanced dual-decoder network for landmark segmentation in AR-guided surgery
X Zhang, S Ali, Y Kang, J Zhu, M Han, L Wang, X Wang, L Zhang
Int. J. Computer Assisted Radiology and Surgery 21 (1), 115–124 Scholar
A Self-Supervised Framework for Improved Generalisability in Ultrasound B-mode Image Segmentation
E Ellis, A Bulpitt, N Parsa, MF Byrne, S Ali
NeeCo: Image Synthesis of Novel Instrument States Based on Dynamic and Deformable 3D Gaussian Reconstruction
T Zeng, J Hu, GL Galindo, S Ali, D Sarikaya, P Valdastri, D Jones
Real-Time Tool Detection in Laparoscopic Datasets for Surgical Training in Low-Resource Settings
O Choudhry, S Ali, CS Biyani, D Jones
Healthcare Technology Letters 12 (1), e70045 Scholar
RobustSurg: Tackling domain generalisation for out-of-distribution surgical scene segmentation
M Ali, M Richards, G Ochoa-Ruiz, S Ali
Point-Guided Latent Diffusion Model for Novel View Synthesis in Laparoscopic Liver Surgery
W Tang, T Chen, Y Espinel, S Farid, E Buc, A Bartoli, S Ali
Healthcare Technology Letters 12 (1), e70032 Scholar
Nested resolution mesh-graph CNN for automated extraction of liver surface anatomical landmarks
X Zhang, J Feng, P Liu, M Han, Y Kang, J Zhu, L Wang, X Wang, S Ali, et al.
Medical Image Analysis, 103825 Scholar
Lesion-Aware Visual-Language Fusion for Automated Image Captioning of Ulcerative Colitis Endoscopic Examinations
AIL Escamilla, G Ochoa, S Ali
MICCAI Workshop on Data Engineering in Medical Imaging Scholar
ESPNet: edge-aware feature shrinkage pyramid for polyp segmentation
R Toman, V Subramanian, S Ali
MICCAI 2025 Scholar
Preoperative to intraoperative deformed liver volumes registration
T Chen, J Borgars, AN Mohamad Shahir, S Farid, S Ali
MIUA 2025 Scholar
7-DoF laparoscopic peg transfer dataset for surgical skill assessment
O Choudhry, S Ali, R Rajasundaram, CS Biyani, D Jones
Frontiers in Medical Technology Scholar
Surg-InvNeRF: Invertible NeRF for 3D tracking and reconstruction in surgical vision
G Loza, J Hu, D Jones, S Ali, P Valdastri
EfficientDet with Knowledge Distillation and Instance Whitening for Real-Time and Generalisable Polyp Detection
R Toman, V Subramanian, S Ali
MIUA 2025 Scholar
Midline-constrained loss in the anatomical landmark segmentation of 3D liver models
AK Abbas, A Gallagher, T Vraimakis, J Borgars, AN Mohamad Shahir, et al.
MIUA 2025 Scholar
Out-of-Distribution Detection in Gastrointestinal Vision by Estimating Nearest Centroid Distance Deficit
S Pokhrel, S Bhandari, S Ali, T Lambrou, A Nguyen, YR Shrestha, et al.
Intraoperative segmentation through deep learning and mask post-processing in laparoscopic liver surgery
J Borgars, J Raja, A Ramakrishnan, AK Abbas, A Gallagher, et al.
MIUA 2025 Scholar
PolypDINO: Adapting DINOv2 for Domain Generalized Polyp Segmentation
M Ali, R Toman, G Ochoa-Ruiz, S Ali
MIUA 2025 Scholar
Two-stream MeshCNN for key anatomical segmentation on the liver surface
X Zhang, S Ali, M Han, Y Kang, X Wang, L Zhang
Int. J. Computer Assisted Radiology and Surgery 20 (7) Scholar
Statistical analysis of infrared spectroscopy for diagnosing inflammatory bowel disease-associated cancer
E Kumi-Barimah, R Toman, S Ali, A Jha, V Subramanian
European Conference on Biomedical Optics Scholar
Solving the long-tailed distribution problem by exploiting the synergies and balance of different techniques
Z Wang, T Lassila, S Ali
An objective comparison of methods for augmented reality in laparoscopic liver resection by preoperative-to-intraoperative image fusion from the MICCAI2022 challenge
S Ali, Y Espinel, Y Jin, P Liu, B Güttner, X Zhang, L Zhang, T Dowrick, et al.
Multi-task learning with cross-task consistency for improved depth estimation in colonoscopy
PEC Solano, A Bulpitt, V Subramanian, S Ali
Validating polyp and instrument segmentation methods in colonoscopy through Medico 2020 and MedAI 2021 Challenges
D Jha, V Sharma, D Banik, D Bhattacharya, K Roy, SA Hicks, NK Tomar, et al.
SSL-CPCD: self-supervised learning with composite pretext-class discrimination for improved generalisability in endoscopic image analysis
Z Xu, J Rittscher, S Ali
Robust and smooth Couinaud segmentation via anatomical structure-guided point-voxel network
X Zhang, S Ali, T Liu, X Zhao, Z Cui, M Han, S Ma, J Zhu, Y Kang, L Wang, et al.
Computers in Biology and Medicine 182, 109202 Scholar
Artificial Intelligence – A Help or Hindrance to Scientific Writing?
P Kron, S Farid, S Ali, P Lodge
Annals of Surgery Scholar
Improving NeRF Representation with No Pose Prior for Novel View Synthesis in Colonoscopy
PE Chavarrias-Solano, B Bhattarai, S Ali
MICCAI Workshop DEMI 2024 Scholar
Exploring anchor-free object detection models for surgical tool detection: a comparative study of Faster-RCNN, YOLOv4, and CenterNet++
C Aparicio, C Guerrero, M Ali Teevno, G Ochoa-Ruiz, S Ali
Mexican International Conference on Artificial Intelligence Scholar
Tackling domain generalization for out-of-distribution endoscopic imaging
MA Teevno, G Ochoa-Ruiz, S Ali
Ultrasound Image Segmentation and its Evaluation using Various Encoder Architectures
E Ellis, A Bulpitt, S Ali
IEEE CBMS 2024 Scholar
Domain generalization for endoscopic image segmentation by disentangling style-content information and superpixel consistency
MA Teevno, R Martinez-Garcia-Pena, G Ochoa-Ruiz, S Ali
Multi-modal detection transformer with data engineering technique to stratify patients with Ulcerative Colitis
A Lopez, H Valencia, G Ochoa-Ruiz, S Ali
IEEE CBMS 2024 Scholar
SSTFB: Leveraging self-supervised pretext learning and temporal self-attention with feature branching for real-time video polyp segmentation
Z Xu, J Rittscher, S Ali
Assessing generalisability of deep learning-based polyp detection and segmentation methods through a computer vision challenge
S Ali, N Ghatwary, D Jha, E Isik-Polat, G Polat, C Yang, W Li, A Galdran, et al.
Real-time surgical tool detection with multi-scale positional encoding and contrastive learning
G Loza, P Valdastri, S Ali
Healthcare Technology Letters Scholar
FANet: A feedback attention network for improved biomedical image segmentation
NK Tomar, D Jha, MA Riegler, HD Johansen, D Johansen, J Rittscher, et al.
IEEE Trans. Neural Networks and Learning Systems 34 (11), 9375–9388 arXivScholar
Bayesian uncertainty-weighted loss for improved generalisability on polyp segmentation task
RS Stone, PE Chavarrias-Solano, AJ Bulpitt, DC Hogg, S Ali
Image captioning for automated grading and understanding of ulcerative colitis
FH Valencia, D Flores-Araiza, O Cerda, V Subramanian, T De Lange, et al.
MICCAI Workshop CaPTion 2023 Scholar
Anatomical-aware point-voxel network for Couinaud segmentation in liver CT
X Zhang, Y Liu, S Ali, X Zhao, M Sun, M Han, T Liu, P Zhai, Z Cui, P Zhang, et al.
MICCAI 2023 Scholar
Vision transformer-based self-supervised learning for ulcerative colitis grading in colonoscopy
A Pyatha, Z Xu, S Ali
MICCAI Workshop DEMI 2023 Scholar
A Client-server Deep Federated Learning for Cross-domain Surgical Image Segmentation
R Subedi, RR Gaire, S Ali, A Nguyen, D Stoyanov, B Bhattarai
A multi-centre polyp detection and segmentation dataset for generalisability assessment
S Ali, D Jha, N Ghatwary, S Realdon, R Cannizzaro, OE Salem, et al.
SUPRA: Superpixel Guided Loss for Improved Multi-Modal Segmentation in Endoscopy
R Martínez-García-Peña, MA Teevno, G Ochoa-Ruiz, S Ali
Why is the winner the best?
M Eisenmann, A Reinke, V Weru, MD Tizabi, F Isensee, TJ Adler, S Ali, et al.
Where do we stand in AI for endoscopic image analysis? Deciphering gaps and future directions
S Ali
npj Digital Medicine 5, 184 Scholar
Biomedical image analysis competitions: The state of current participation practice
M Eisenmann, A Reinke, V Weru, MD Tizabi, F Isensee, TJ Adler, et al.
Patch-level instance-group discrimination with pretext-invariant learning for colitis scoring
Z Xu, S Ali, S Gupta, S Leedham, JE East, J Rittscher
UNet-eVAE: Iterative Refinement Using VAE Embodied Learning for Endoscopic Image Segmentation
S Gupta, S Ali, Z Xu, B Bhattarai, B Turney, J Rittscher
MLMI 2022 (MICCAI Workshop) Scholar
Improving artifact detection in endoscopic video frames using deep learning techniques
PE Chavarrias-Solano, M Ali-Teevno, G Ochoa-Ruiz, S Ali
Mexican International Conference on Artificial Intelligence Scholar
A semi-supervised Teacher-Student framework for surgical tool detection and localization
M Ali, G Ochoa-Ruiz, S Ali
Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization arXivScholar
Real-time instance segmentation of surgical instruments using attention and multi-scale feature fusion
JCÁ Cerón, GO Ruiz, L Chang, S Ali
Multi-class motion-based semantic segmentation for ureteroscopy and laser lithotripsy
S Gupta, S Ali, L Goldsmith, B Turney, J Rittscher
Computerized Medical Imaging and Graphics 101, 102112 arXivScholar
Self-supervised approach for a fully assistive esophageal surveillance: Quality, anatomy and neoplasia guidance
Z Xu, S Ali, N Celik, A Bailey, B Braden, J Rittscher
MICCAI Workshop CaPTion 2022 Scholar
Knowledge distillation with a class-aware loss for endoscopic disease detection
PE Chavarrias-Solano, MA Teevno, G Ochoa-Ruiz, S Ali
A comprehensive survey on recent deep learning-based methods applied to surgical data
M Ali, RMG Pena, GO Ruiz, S Ali
TGANet: Text-guided attention for improved polyp segmentation
NK Tomar, D Jha, U Bagci, S Ali
GMSRF-Net: An improved generalizability with global multi-scale residual fusion network for polyp segmentation
A Srivastava, S Chanda, D Jha, U Pal, S Ali
Meta-learning with implicit gradients in a few-shot setting for medical image segmentation
R Khadka, D Jha, S Hicks, V Thambawita, MA Riegler, S Ali, P Halvorsen
Additive angular margin loss and model scaling network for optimised colitis scoring
Z Xu, S Ali, J East, J Rittscher
IEEE ISBI 2022 Scholar
Endoscopic vision challenge 2022
A Zia, X Liu, K Bhattacharyya, Z Wang, M Berniker, A Jarc, C Nwoye, et al.
MICCAI 2022 Scholar
MSRF-Net: A multi-scale residual fusion network for biomedical image segmentation
A Srivastava, D Jha, S Chanda, U Pal, HD Johansen, D Johansen, et al.
IEEE J. Biomedical and Health Informatics 26 (5), 2252–2263 arXivScholar
Iterative deep learning for improved segmentation of endoscopic images
S Ali, NK Tomar
Nordic Machine Intelligence 1 (1), 38–40 Scholar
Assessing YOLACT++ for real time and robust instance segmentation of medical instruments in endoscopic procedures
JCÁ Cerón, L Chang, GO Ruiz, S Ali
EndoUDA: A modality independent segmentation approach for endoscopy imaging
N Celik, S Ali, S Gupta, B Braden, J Rittscher
A pilot study on automatic three-dimensional quantification of Barrett's esophagus for risk stratification and therapy monitoring
S Ali, A Bailey, S Ash, M Haghighat, P Allan, T Ambrose, et al.
Gastroenterology 161 (3), 865–878 Scholar
Exploring deep learning methods for real-time surgical instrument segmentation in laparoscopy
D Jha, S Ali, NK Tomar, MA Riegler, D Johansen, HD Johansen, et al.
Improved artifact detection in endoscopy imaging through profile pruning
Z Xu, S Ali, S Gupta, N Celik, J Rittscher
MIUA 2021 Scholar
Improving Generalizability in Polyp Segmentation using Ensemble Convolutional Neural Network
NK Tomar, N Ibtehaz, D Jha, P Halvorsen, S Ali
EndoCV 2021 Workshop Scholar
Spectral endoscopy enhances contrast for neoplasia in surveillance of Barrett's esophagus
DJ Waterhouse, W Januszewicz, S Ali, RC Fitzgerald, M Di Pietro, et al.
Cancer Research 81 (12), 3415–3425 Scholar
Real-time polyp segmentation using U-net with IoU loss
G Batchkala, S Ali
MediaEval 2021 (CEUR-WS) Scholar
NanoNet: Real-time polyp segmentation in video capsule endoscopy and colonoscopy
D Jha, NK Tomar, S Ali, MA Riegler, HD Johansen, D Johansen, et al.
A comprehensive analysis of classification methods in gastrointestinal endoscopy imaging
D Jha, S Ali, S Hicks, V Thambawita, H Borgli, PH Smedsrud, T de Lange, et al.
Medical Image Analysis 70, 102007 Scholar
Deep learning for detection and segmentation of artefact and disease instances in gastrointestinal endoscopy
S Ali, M Dmitrieva, N Ghatwary, S Bano, G Polat, A Temizel, A Krenzer, et al.
Real-time polyp detection, localization and segmentation in colonoscopy using deep learning
D Jha, S Ali, NK Tomar, HD Johansen, D Johansen, J Rittscher, et al.
A deep learning framework for quality assessment and restoration in video endoscopy
S Ali, F Zhou, A Bailey, B Braden, JE East, X Lu, J Rittscher
Kvasir-Instrument: Diagnostic and therapeutic tool segmentation dataset in gastrointestinal endoscopy
D Jha, S Ali, K Emanuelsen, SA Hicks, E Garcia-Ceja, MA Riegler, et al.
No papers match that search.
Medical Image Understanding and Analysis: 29th Annual Conference, MIUA 2025, Leeds (Proceedings)
S Ali, DC Hogg, M Peckham (eds.)
Springer Nature
Cancer Prevention, Detection, and Intervention: CaPTion 2024 (MICCAI Workshop proceedings)
S Ali, F van der Sommen, BW Papież, N Ghatwary, Y Jin, I Kolenbrander (eds.)
Springer Nature
Cancer Prevention Through Early Detection: CaPTion 2023 (MICCAI Workshop proceedings)
S Ali, F van der Sommen, M van Eijnatten, BW Papież, Y Jin, et al. (eds.)
Springer Nature
Data Engineering in Medical Imaging: DEMI 2023 (MICCAI Workshop proceedings)
B Bhattarai, S Ali, A Rau, A Nguyen, A Namburete, R Caramalau, et al. (eds.)
Springer Nature
Cancer Prevention Through Early Detection: CaPTion 2022 (MICCAI Workshop proceedings)
S Ali, F van der Sommen, BW Papież, M van Eijnatten, Y Jin, et al. (eds.)
Springer Nature
Quality assessment in video endoscopy
J Rittscher, S Ali, A Bailey, JE East, B Braden, F Zhou, X Lu
US Patent 12,249,065
Ureteroscopy imaging system and methods
S Gupta, S Ali, J Rittscher, B Turney, NP Rauniyar, A Ray, et al.
US Patent App. 18/588,865 and 18/581,220
Quantification of Barrett's oesophagus
S Ali, J Rittscher, B Braden, JE East, A Bailey
US Patent App. 18/028,796
| Years | Project | Funder | Amount |
|---|---|---|---|
| 2025–2028 | Real-time High-Fidelity Augmented Reality in Laparoscopic Liver ResectionNew Investigator Award · UKRI914 | EPSRC | £739,397 |
| 2025–2027 | Leveraging multi-modality data for targeted biopsy and risk stratification of patients with inflammatory bowel diseaseSpringboard Award | Academy of Medical Sciences | £349,407 |
| 2024–2026 | AI-assisted identification of dysplastic polyps during colonoscopic surveillance in patients with colonic IBD | Crohn's & Colitis UK | £98,691 |
| 2026–2027 | Fibre 3D Endoscopy for Improved Clinical Surveillance | EPSRC | £86,809 |
| 2025–2026 | Holistic 3D vision of the gastrointestinal tract to support clinical decisionsMedTech Place-Based Impact Acceleration Account | EPSRC | £46,481 |
| 2024–2025 | Augmented reality in liver laparoscopy leveraging multi-modal imaging dataLeeds BRC Pump-Priming | NIHR | £39,890 |
| 2026 | Functional imaging in liver tissue maps with multi-modal MRI and medically informed machine learningRadNet Leeds Development Fund | Cancer Research UK | £29,297 |
| 2025–2026 | Artificial Intelligence for Surgical Training Towards Safer and Effective Sub-mucosal DissectionWith Tec de Monterrey and University of Exeter | Worldwide Universities Network | £10,000 |
| 2024 | Novel robust computer vision methods and synthetic datasets for minimally invasive surgery | Worldwide Universities Network | £10,000 |
Source: ORCID 0000-0003-1313-3542.
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